Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.67 |
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | PPARD | Q03181 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694438 | 1.00 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| SCHEMBL10691842 | 1.00 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| SCHEMBL10687830 | 1.00 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| SCHEMBL10693120 | 1.00 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| SCHEMBL10687786 | 1.00 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| SCHEMBL3033071 | 1.00 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| Tomelukast SCHEMBL3944 | 0.99 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| SCHEMBL10693436 | 0.96 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| SCHEMBL9777248 | 0.90 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1LMNAMEN1GLA | |
| SCHEMBL9643112 | 0.89 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1LMNAMEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769482-A | Cyano and thiocyano intermediates | ELI LILLY AND COMPANY (US) | 1988-09-06 | — | — | US | disclosed |
| EP-0108592-B1 | LEUKOTRIENE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1987-09-30 | — | — | EP | disclosed |
| US-4661505-A | 4-(4-ACETYL-3-HYDROXY-2-PROPYLPHENOXY) ALKANOIC ACIDS, TETRAZOLES, AND DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-04-28 | — | — | US | disclosed |
| EP-0108592-A1 | Leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1984-05-16 | — | — | EP | disclosed |