Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 9/20 | 0.43 |
| ▸ | ATP4B | P51164 | 9/20 | 0.43 |
| ▸ | ATP1A1 | P05023 | 6/20 | 0.43 |
| ▸ | ATP1B1 | P05026 | 6/20 | 0.43 |
| ▸ | ATP1A3 | P13637 | 6/20 | 0.43 |
| ▸ | ATP1B2 | P14415 | 6/20 | 0.43 |
| ▸ | ATP1A2 | P50993 | 6/20 | 0.43 |
| ▸ | ATP1B3 | P54709 | 6/20 | 0.43 |
| ▸ | FXYD2 | P54710 | 6/20 | 0.43 |
| ▸ | ATP1A4 | Q13733 | 6/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 7/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10335163 | 0.89 | ATP4A (0.41) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL10335419 | 0.89 | ATP4A (0.48) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL8503340 | 0.89 | CYP2C9 (0.46) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL9527378 | 0.88 | ATP4A (0.54) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL14648568 | 0.87 | ATP4A (0.40) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL10616885 | 0.87 | CYP2C9 (0.41) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL10616894 | 0.87 | CYP2C9 (0.41) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL23988598 | 0.87 | ATP4A (0.41) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL23988516 | 0.87 | ATP4A (0.41) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL10480713 | 0.87 | ATP4A (0.41) | ATP4AATP4BATP1A1ATP1B1ATP1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4725691-A | CHEMICAL INTERMEDIATES; ANTISECRETORY AGENTS | AKTIEBOLAGET HASSLE (SE) | 1988-02-16 | — | — | US | disclosed |
| US-4636499-A | GASTRIC ANTISECRETORY | AKTIEBOLAGET HASSLE (SE) | 1987-01-13 | — | — | US | disclosed |
| EP-0171372-A1 | Sulphenamides, processes for their preparation and their use in the manufacture of pharmaceutical preparations | Aktiebolaget Hässle (SE) | 1986-02-12 | — | — | EP | disclosed |