SCHEMBL10692040

SCHEMBL10692040

CC(Oc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1)C(N)=O

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.65
LMNA P02545 5/20 0.60
ALDH1A1 P00352 3/20 0.59
FFAR1 O14842 1/20 0.57
LIPE Q05469 1/20 0.56
KMT2A Q03164 2/20 0.55
MEN1 O00255 1/20 0.55
RAB9A P51151 1/20 0.53
ATM Q13315 1/20 0.52
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C19 P33261 1/20 0.51
HTT P42858 2/20 0.51
POLB P06746 1/20 0.51
MAPT P10636 1/20 0.51
KDM4E B2RXH2 1/20 0.51
HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Haloxyfop SCHEMBL29426466 0.90 SMN1; SMN2 (0.65) SMN1; SMN2LMNAALDH1A1FFAR1LIPE
Haloxyfop-R-Methyl SCHEMBL29730427 0.90 SMN1; SMN2 (0.65) SMN1; SMN2LMNAALDH1A1FFAR1LIPE
Haloxyfop-R-Methyl SCHEMBL119996 0.90 SMN1; SMN2 (0.65) SMN1; SMN2LMNAALDH1A1FFAR1LIPE
SCHEMBL9449585 0.90 SMN1; SMN2 (0.61) SMN1; SMN2LMNAALDH1A1FFAR1LIPE
SCHEMBL30749500 0.90 SMN1; SMN2 (0.61) SMN1; SMN2LMNAALDH1A1FFAR1LIPE
Haloxyfop SCHEMBL29792114 0.90 SMN1; SMN2 (0.65) SMN1; SMN2LMNAALDH1A1FFAR1LIPE
Haloxyfop SCHEMBL3675562 0.90 SMN1; SMN2 (0.65) SMN1; SMN2LMNAALDH1A1FFAR1LIPE
Haloxyfop SCHEMBL33627 0.90 SMN1; SMN2 (0.65) SMN1; SMN2LMNAALDH1A1FFAR1LIPE
SCHEMBL9363159 0.90 SMN1; SMN2 (0.61) SMN1; SMN2LMNAALDH1A1FFAR1LIPE
Haloxyfop SCHEMBL1560810 0.90 SMN1; SMN2 (0.65) SMN1; SMN2LMNAALDH1A1FFAR1LIPE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4753673-A GRASSY WEEDS THE DOW CHEMICAL COMPANY (US) 1988-06-28 US disclosed
US-4628099-A INTERMEDIATES FOR HERBICIDES THE DOW CHEMICAL COMPANY (US) 1986-12-09 US disclosed
US-4551170-A Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanols and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1985-11-05 US disclosed
US-4491468-A Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanenitriles and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1985-01-01 US disclosed
US-4479001-A Trifluoromethyl pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1984-10-23 US disclosed
EP-0061112-A1 Compounds and method for selectively controlling grassy weeds in broadleaved crops THE DOW CHEMICAL COMPANY (US) 1982-09-29 EP disclosed
US-4330321-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1982-05-18 US disclosed
EP-0000483-B1 TRIFLUOROMETHYL PYRIDINYL(OXY/THIO)PHENOXY PROPANOIC ACIDS AND PROPANOLS AND DERIVATIVES THEREOF THE DOW CHEMICAL COMPANY (US) 1981-10-14 EP disclosed
EP-0000483-A1 Trifluoromethyl pyridinyl(oxy/thio)phenoxy propanoic acids and propanols and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1979-02-07 EP disclosed