SCHEMBL10692223

SCHEMBL10692223

CCN(C=O)CC.Nc1ccccc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.56
ALDH1A1 P00352 5/20 0.39
HSD17B10 Q99714 2/20 0.36
TP53 P04637 1/20 0.36
NR4A2 P43354 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NOS3 P29474 2/20 0.33
NOS1 P29475 2/20 0.33
NOS2 P35228 2/20 0.33
LMNA P02545 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
AOC3 Q16853 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NISCH Q9Y2I1 1/20 0.33
PNMT P11086 1/20 0.32
CYP3A4 P08684 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10691258 0.80 TSHR (0.39) TSHRALDH1A1HSD17B10NOS3NOS1
Aniline SCHEMBL10692374 0.79 TSHR (0.46) TSHRALDH1A1HSD17B10MEN1KMT2A
Formic Acid SCHEMBL27489350 0.76 TSHR (0.71) TSHRALDH1A1HSD17B10TP53NR4A2
Alcohol SCHEMBL11612801 0.76 TSHR (0.71) TSHRALDH1A1HSD17B10NR4A2NOS3
Ethane SCHEMBL27617757 0.75 TSHR (0.88) TSHRALDH1A1TP53NR4A2LMNA
Formic Acid Methyl Ester SCHEMBL28217042 0.75 TSHR (0.62) TSHRALDH1A1HSD17B10NR4A2MEN1
SCHEMBL29472208 0.74
SCHEMBL25495 0.74
Formaldehyde SCHEMBL6858464 0.73 TSHR (0.83) TSHRALDH1A1TP53NR4A2LMNA
Methyl Alcohol SCHEMBL27890061 0.73 TSHR (0.83) TSHRALDH1A1TP53NR4A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed