Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC5 | O15392 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 5/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HK1 | P19367 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1932280 | 0.77 | BACE1 (0.57) | BACE1EGFRKMT2A | |
| SCHEMBL9654279 | 0.74 | BIRC5 (1.00) | BIRC5MAP4K4GABRG2GABRB3GABRA5 | |
| SCHEMBL29931577 | 0.74 | BIRC5 (1.00) | BIRC5MAP4K4GABRG2GABRB3GABRA5 | |
| SCHEMBL1600169 | 0.73 | BACE1 (0.57) | BACE1EGFRMAPTALDH1A1KDM4E | |
| SCHEMBL29987438 | 0.73 | BACE1 (0.57) | BACE1EGFRMAPTALDH1A1KDM4E | |
| SCHEMBL629471 | 0.72 | BACE1 (0.59) | BACE1RAB9AMAP4K4NPC1KMT2A | |
| SCHEMBL27440988 | 0.72 | RAB9A (0.50) | BIRC5MAPTRAB9AALDH1A1HPGD | |
| SCHEMBL18202554 | 0.71 | MAPK1 (0.44) | — | |
| SCHEMBL10686110 | 0.70 | BACE1 (0.64) | BACE1MAP4K4 | |
| SCHEMBL21243723 | 0.69 | KDM4E (0.49) | BIRC5BACE1MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720500-A | N-1,8-naphthyridin-2-yl amides useful as immunostimulants | RHONE-POULENC SANTE (FR) | 1988-01-19 | — | — | US | disclosed |