Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431487 | 0.84 | CNR1 (0.57) | LMNAHPGDALDH1A1POLBHTT | |
| SCHEMBL4207501 | 0.81 | ERCC1 (0.51) | LMNAHPGDALDH1A1CYP2C19POLB | |
| SCHEMBL10418937 | 0.81 | HPGD (0.51) | LMNAHPGDALDH1A1CYP2C19POLB | |
| SCHEMBL9645001 | 0.80 | NAAA (0.57) | NAAALMNAHPGDMAPK1MAPT | |
| SCHEMBL7163533 | 0.78 | KDM4E (0.41) | LMNAHPGDALDH1A1MAPK1POLB | |
| SCHEMBL12676690 | 0.77 | NAAA (0.66) | NAAALMNAHPGDALDH1A1MAPK1 | |
| SCHEMBL1615778 | 0.77 | NAAA (0.66) | NAAALMNAHPGDALDH1A1MAPK1 | |
| SCHEMBL12676604 | 0.77 | NAAA (0.66) | NAAALMNAHPGDALDH1A1MAPK1 | |
| SCHEMBL11628924 | 0.77 | NAAA (0.57) | NAAALMNAHPGDALDH1A1MAPK1 | |
| SCHEMBL23295869 | 0.76 | HPGD (0.43) | LMNAHPGDALDH1A1CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |