Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81650 | 0.75 | NISCH (0.59) | NISCHALDH1A1SMN1; SMN2PDE4APDE4B | |
| Hydrochloric Acid SCHEMBL1536214 | 0.72 | NISCH (0.56) | NISCHALDH1A1SMN1; SMN2PDE4APDE4B | |
| SCHEMBL28425230 | 0.72 | NISCH (0.56) | NISCHALDH1A1SMN1; SMN2PDE4APDE4B | |
| SCHEMBL5448437 | 0.68 | NISCH (0.46) | NISCHALDH1A1SMN1; SMN2PDE4APDE4B | |
| SCHEMBL434461 | 0.67 | NISCH (0.42) | NISCHALDH1A1SMN1; SMN2PDE4APDE4B | |
| SCHEMBL19097188 | 0.65 | NISCH (0.47) | NISCHALDH1A1SMN1; SMN2PDE4APDE4B | |
| SCHEMBL4108846 | 0.65 | NISCH (0.41) | NISCHALDH1A1SMN1; SMN2PDE4APDE4B | |
| SCHEMBL19127750 | 0.64 | NISCH (0.42) | NISCHALDH1A1SMN1; SMN2PDE4APDE4B | |
| SCHEMBL9186148 | 0.64 | NISCH (0.48) | NISCHALDH1A1SMN1; SMN2PDE4APDE4B | |
| SCHEMBL4190354 | 0.64 | NISCH (0.55) | NISCHALDH1A1SMN1; SMN2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4781866-A | Process for producing amidine sulfonic acid intermediates for guanidines | MCNEILAB, INC. (US) | 1988-11-01 | — | — | US | disclosed |