Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81650 | 0.78 | NISCH (0.59) | NISCHMTORADKPDE4APDE4B | |
| SCHEMBL28425230 | 0.75 | NISCH (0.56) | NISCHMTORADKPDE4APDE4B | |
| Hydrochloric Acid SCHEMBL1536214 | 0.75 | NISCH (0.56) | NISCHMTORADKPDE4APDE4B | |
| SCHEMBL4108846 | 0.68 | NISCH (0.41) | NISCHMTORADKPDE4APDE4B | |
| SCHEMBL10692386 | 0.67 | NISCH (0.46) | NISCHMTORADKPDE4APDE4B | |
| SCHEMBL20357190 | 0.67 | NISCH (0.39) | NISCHMTORADKPDE4APDE4B | |
| SCHEMBL12131223 | 0.67 | NISCH (0.43) | NISCHMTORADKPDE4APDE4B | |
| SCHEMBL9900117 | 0.65 | NISCH (0.38) | NISCHMTORADKPDE4APDE4B | |
| SCHEMBL2653482 | 0.65 | KDM4E (0.48) | MTORALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29040730 | 0.65 | ALDH1A1 (0.42) | NISCHMTORADKPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766672-B1 | ARYLSULFONAMIDO-SUBSTITUTED HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE INHIBITORS | NOVARTIS AG (CH) | 2000-10-04 | — | — | EP | claimed |
| US-5981537-A | USEFUL IN THE TREATMENT OF INDIVIDUALS WHO ARE HIV POSITIVE | PHARMACIA & UPJOHN COMPANY (US) | 1999-11-09 | — | — | US | claimed |
| CN-114685331-B | Process for producing 1, 2-dithioethane compound | 华南理工大学 | 2024-07-09 | — | — | CN | disclosed |
| EP-4366717-A1 | BROAD-SPECTRUM ANTIVIRAL DRUGS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2024-05-15 | — | — | EP | disclosed |
| US-11958871-B2 | Inhibitors of bacterial glutaminyl cyclases for use in the treatment of periodontal and related diseases | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2024-04-16 | — | — | US | disclosed |
| CN-114685425-B | Preparation method of thiacrown ether compound | 广州自远生物科技有限公司 | 2024-02-27 | — | — | CN | disclosed |
| WO-2024039250-A1 | METHANOGEN INHIBITORS | PASTORAL GREENHOUSE GAS RESEARCH LIMITED (NZ) | 2024-02-22 | — | — | WO | disclosed |
| CN-115197046-B | Halogenation method of unsaturated hydrocarbon | 华南理工大学 | 2023-12-15 | — | — | CN | disclosed |
| US-20230122243-A1 | Heteroaromatic inhibitors of astacin proteinases | VIVORYON THERAPEUTICS N.V. (DE) | 2023-04-20 | — | — | US | disclosed |
| WO-2023281063-A1 | BROAD-SPECTRUM ANTIVIRAL DRUGS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2023-01-12 | — | — | WO | disclosed |
| CN-115197046-A | Halogenation method of unsaturated hydrocarbon | 华南理工大学 | 2022-10-18 | — | — | CN | disclosed |
| EP-1400518-B1 | HETEROCYCLIC COMPOUND DERIVATIVES AND MEDICINES | NIPPON SHINYAKU CO LTD (JP) | 2007-01-17 | — | — | EP | disclosed |
| US-20060189645-A1 | Novel 6-phenylphenantridines | ALTANA PHARMA AG (DE) | 2006-08-24 | — | — | US | disclosed |
| US-6787570-B2 | ADMINISTERING AN AROMATIC OR HETEROAROMATIC SUBSTITUTED TERTIARYAMINE COMPOUND TO TREAT ATHEROSCLEROSIS, DYSLIPIDEMIA, AND OTHER CORONARY ARTERY DISEASES | PFIZER, INC. | 2004-09-07 | — | — | US | disclosed |
| US-20040162318-A1 | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases | VIROPHARMA INCORPORATED | 2004-08-19 | — | — | US | disclosed |
| US-20040087601-A1 | Pyrimidine derivatives as IL-8 receptor antagonists | PHARMACOPEIA, LLC | 2004-05-06 | — | — | US | disclosed |
| US-20030191306-A1 | Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-10-09 | — | — | US | disclosed |
| US-5410052-A | Useful for extraction of ligand such as molecular oxygen from fluid environment and for release of such ligand | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-04-25 | — | — | US | disclosed |
| US-4959135-A | OXYGEN | AQUANAUTICS CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |
| WO-1988006641-A1 | POLYALKYLAMINE COMPLEXES FOR LIGAND EXTRACTION AND GENERATION | AQUANAUTICS CORPORATION (US) | 1988-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230122243-A1 | Heteroaromatic inhibitors of astacin proteinases | BMP1, DPEP1, MEP1A | NISCH 2297/4885MTOR 3952/4885ADK 3974/4885 |
| US-11958871-B2 | Inhibitors of bacterial glutaminyl cyclases for use in the treatment of periodontal and related diseases | GMPS, GLS, QPCT | NISCH 4311/4885MTOR 2934/4885ADK 1705/4885 |
| US-20030191306-A1 | Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, DBI, MTTP | NISCH 1401/4885MTOR 3508/4885ADK 1691/4885 |
| US-20040087601-A1 | Pyrimidine derivatives as IL-8 receptor antagonists | CXCL8, IL1RN, IL18 | NISCH 2148/4885MTOR 2130/4885ADK 219/4885 |
| US-20060189645-A1 | Novel 6-phenylphenantridines | PDE4B, PDE4A, PDE4D | NISCH 2355/4885MTOR 4277/4885ADK 1703/4885 |
| US-20040162318-A1 | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases | BBOX1, HAVCR2, CYP2E1 | NISCH 41/4885MTOR 2557/4885ADK 4437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.