Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692220 | 1.00 | ATM (0.49) | ATMALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10692539 | 1.00 | ATM (0.49) | ATMALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10694325 | 0.86 | EDNRA (0.49) | ATMKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL10694317 | 0.86 | EDNRA (0.49) | ATMKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL10694322 | 0.86 | EDNRA (0.49) | ATMKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL10655154 | 0.82 | ABCB1 (0.39) | HTTCYP2C9 | |
| SCHEMBL10655141 | 0.82 | ABCB1 (0.39) | HTTCYP2C9 | |
| SCHEMBL10656603 | 0.82 | ABCB1 (0.39) | HTTCYP2C9 | |
| SCHEMBL10655166 | 0.82 | ABCB1 (0.39) | HTTCYP2C9 | |
| SCHEMBL10695009 | 0.82 | ABCB1 (0.39) | HTTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264234-A1 | Novel benzofurans and a novel method of preparation | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-04-20 | — | — | EP | disclosed |