Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.49 |
| ▸ | EDNRB | P24530 | 2/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694322 | 1.00 | EDNRA (0.49) | EDNRAEDNRBGABRA1GABRB2ATM | |
| SCHEMBL10694325 | 1.00 | EDNRA (0.49) | EDNRAEDNRBGABRA1GABRB2ATM | |
| SCHEMBL10692553 | 0.86 | ATM (0.49) | ATMMEN1KMT2AMAPTNPC1 | |
| SCHEMBL10692539 | 0.86 | ATM (0.49) | ATMMEN1KMT2AMAPTNPC1 | |
| SCHEMBL10692220 | 0.86 | ATM (0.49) | ATMMEN1KMT2AMAPTNPC1 | |
| SCHEMBL10655154 | 0.85 | ABCB1 (0.39) | EDNRAHTT | |
| SCHEMBL10655166 | 0.85 | ABCB1 (0.39) | EDNRAHTT | |
| SCHEMBL10656603 | 0.85 | ABCB1 (0.39) | EDNRAHTT | |
| SCHEMBL10655141 | 0.85 | ABCB1 (0.39) | EDNRAHTT | |
| SCHEMBL10695009 | 0.85 | ABCB1 (0.39) | EDNRAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264234-A1 | Novel benzofurans and a novel method of preparation | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-04-20 | — | — | EP | disclosed |