Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632936 | 0.84 | CYP4A11 (0.44) | CA2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9632567 | 0.82 | GRIN2D (0.35) | CA2CA1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29291452 | 0.82 | GRIN2D (0.49) | CA2CA1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9632543 | 0.81 | CA2 (0.46) | CA2ALDH1A1HSD17B10ESR1ADRA2A | |
| SCHEMBL8732972 | 0.80 | ESR1 (0.50) | CA2CA1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL986697 | 0.80 | AKR1C3 (0.55) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8729054 | 0.80 | ESR1 (0.50) | CA2CA1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8732968 | 0.80 | ESR1 (0.50) | CA2CA1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8729056 | 0.80 | ESR1 (0.50) | CA2CA1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9625356 | 0.79 | RARB (0.53) | CA2CA1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262348-A2 | Process for the preparation of N-substituted morpholine and piperidine derivatives | HÜLS AKTIENGESELLSCHAFT (DE) | 1988-04-06 | — | — | EP | disclosed |