Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 1/20 | 0.60 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.60 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692625 | 0.78 | CHEK1 (0.56) | CHEK1LIMK1CDK5CLK4ADORA3 | |
| SCHEMBL27961282 | 0.77 | PKN1 (0.79) | PKN1PKN2ADORA3MGAMGAA | |
| SCHEMBL6663139 | 0.76 | MGAM (0.55) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL5204856 | 0.75 | PKN1 (0.63) | PKN1PKN2ADORA3MGAMGAA | |
| SCHEMBL6332531 | 0.75 | PKN1 (0.61) | PKN1PKN2ADORA3MGAMGAA | |
| SCHEMBL31049579 | 0.74 | PKN1 (0.73) | PKN1PKN2ADORA3MGAMGAA | |
| SCHEMBL7886398 | 0.74 | PKN1 (0.73) | PKN1PKN2ADORA3MGAMGAA | |
| SCHEMBL10172967 | 0.74 | PKN1 (0.73) | PKN1PKN2ADORA3MGAMGAA | |
| SCHEMBL1013588 | 0.73 | PKN1 (0.60) | PKN1PKN2ADORA3MGAMGAA | |
| SCHEMBL29411967 | 0.73 | PARP1 (0.63) | PKN1PKN2CLK4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252028-A1 | Process for preparing nitrofurylbenzimidazoles and pharmaceutical compositions having antimycotic, antibacterial and antitubercular activities containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-01-07 | — | — | EP | claimed |
| EP-0252028-A1 | Process for preparing nitrofurylbenzimidazoles and pharmaceutical compositions having antimycotic, antibacterial and antitubercular activities containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-01-07 | — | — | EP | disclosed |
| EP-0252028-A1 | Process for preparing nitrofurylbenzimidazoles and pharmaceutical compositions having antimycotic, antibacterial and antitubercular activities containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-01-07 | — | — | EP | disclosed |
| EP-0252028-A1 | Process for preparing nitrofurylbenzimidazoles and pharmaceutical compositions having antimycotic, antibacterial and antitubercular activities containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-01-07 | — | — | EP | disclosed |