Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692619 | 0.78 | PKN1 (0.60) | CHEK1LIMK1CDK5CLK4ALOX5 | |
| SCHEMBL1895139 | 0.77 | MEN1 (0.56) | ADORA3KMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL5204870 | 0.75 | MEN1 (0.43) | ADORA3ADORA2BKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6332534 | 0.75 | MAPT (0.51) | ADORA3KMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL3558120 | 0.74 | ALDH1A1 (0.49) | CHEK1LIMK1CDK5CLK4ALOX5 | |
| SCHEMBL1013587 | 0.73 | MAPT (0.53) | KMT2AKDM4ESMN1; SMN2MEN1MAPT | |
| SCHEMBL31049562 | 0.73 | GUSB (0.53) | KMT2AKDM4ESMN1; SMN2MEN1MAPT | |
| SCHEMBL1900026 | 0.73 | HPGD (0.54) | ADORA3KMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL11086043 | 0.72 | ALDH1A1 (0.45) | CHEK1LIMK1CDK5CLK4ALOX5 | |
| SCHEMBL1201707 | 0.72 | TYMS (0.56) | CDK5KMT2AKDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252028-A1 | Process for preparing nitrofurylbenzimidazoles and pharmaceutical compositions having antimycotic, antibacterial and antitubercular activities containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-01-07 | — | — | EP | claimed |
| EP-0252028-A1 | Process for preparing nitrofurylbenzimidazoles and pharmaceutical compositions having antimycotic, antibacterial and antitubercular activities containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-01-07 | — | — | EP | disclosed |
| EP-0252028-A1 | Process for preparing nitrofurylbenzimidazoles and pharmaceutical compositions having antimycotic, antibacterial and antitubercular activities containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-01-07 | — | — | EP | disclosed |
| EP-0252028-A1 | Process for preparing nitrofurylbenzimidazoles and pharmaceutical compositions having antimycotic, antibacterial and antitubercular activities containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-01-07 | — | — | EP | disclosed |