Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | FCER2 | P06734 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692379 | 0.89 | MME (0.70) | MMEALDH1A1ACEHPGDMAPK1 | |
| SCHEMBL10953351 | 0.78 | MME (0.74) | MMEALDH1A1ACEHPGDMAPK1 | |
| SCHEMBL10691235 | 0.75 | CYP1A2 (0.47) | MMEMMP1FCER2ALDH1A1ACE | |
| SCHEMBL2127131 | 0.74 | MMP2 (0.54) | NPC1RAB9A | |
| SCHEMBL11911567 | 0.74 | NPC1 (0.53) | NPC1RAB9A | |
| SCHEMBL859814 | 0.74 | MMP2 (0.54) | NPC1RAB9A | |
| SCHEMBL10957779 | 0.73 | CYP3A4 (0.67) | MMEMMP1FCER2ALDH1A1ACE | |
| SCHEMBL9979326 | 0.73 | GAA (0.58) | MMEMMP1FCER2ALDH1A1HPGD | |
| SCHEMBL15265396 | 0.72 | NPC1 (0.57) | CYP1A2CYP2D6CYP2C9CYP2C19NPC1 | |
| SCHEMBL7325857 | 0.71 | MME (1.00) | MMEALDH1A1ACEHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738803-A | ENZYME INHIBITORS | ROQUES BERNARD (FR) | 1988-04-19 | — | — | US | disclosed |
| US-4618708-A | ENKEPHALINASE INHIBITOR, ANALGESICS, ANTIDEPRESSANT, ANTIDIARRHEA, OR HYPOTENSIVE AGENT | ROQUES BERNARD (FR) | 1986-10-21 | — | — | US | disclosed |