SCHEMBL10692667

SCHEMBL10692667

Cc1ccc(N[C@H](Cc2ccccc2)C(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.55
MMP9 P14780 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.52
MAPK1 P28482 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
FPR2 P25090 6/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
ITGB1 P05556 1/20 0.49
ITGA4 P13612 1/20 0.49
NPR3 P17342 1/20 0.49
ATM Q13315 1/20 0.49
MME P08473 1/20 0.49
PSMB5 P28074 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7100965 1.00 PPARG (0.55) PPARGMMP9L3MBTL1MAPK1NPSR1
SCHEMBL10690483 0.94 PPARG (0.51) PPARGMMP9L3MBTL1MAPK1NPSR1
SCHEMBL10690468 0.94 PPARG (0.51) PPARGMMP9L3MBTL1MAPK1NPSR1
SCHEMBL21373234 0.92 PPARG (0.49) PPARGMMP9L3MBTL1MAPK1NPSR1
SCHEMBL21373232 0.92 PPARG (0.49) PPARGMMP9L3MBTL1MAPK1NPSR1
SCHEMBL10690475 0.90 MMP9 (0.48) PPARGMMP9L3MBTL1MAPK1NPSR1
Hydrochloric Acid SCHEMBL1499448 0.89 MMP9 (0.47) PPARGMMP9L3MBTL1MAPK1NPSR1
SCHEMBL1533647 0.88 PPARG (0.58) PPARGMMP9NPSR1FPR2MME
SCHEMBL1533645 0.88 PPARG (0.58) PPARGMMP9NPSR1FPR2MME
SCHEMBL6250861 0.88 PPARG (0.58) PPARGMMP9NPSR1FPR2MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63054321-A None JP disclosed
JP-S6354321-A BLOOD SUGAR LOWERING AGENT AJINOMOTO CO INC 1988-03-08 JP disclosed