Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | LDHA | P00338 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693966 | 0.95 | CYP19A1 (0.61) | CYP19A1MAPTNPC1CYP3A4ADORA3 | |
| SCHEMBL6124100 | 0.88 | CYP19A1 (0.77) | CYP19A1MAPTADORA3KDM4EALDH1A1 | |
| SCHEMBL28522066 | 0.83 | CYP19A1 (0.67) | CYP19A1MAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL14047475 | 0.83 | PPARG (0.53) | CYP19A1MAPTNPC1CYP3A4MAPK1 | |
| SCHEMBL10525226 | 0.80 | CYP19A1 (0.61) | CYP19A1MAPTNPC1MAPK1KDM4E | |
| SCHEMBL10815794 | 0.80 | CYP19A1 (0.66) | CYP19A1MAPTNPC1MAPK1RAB9A | |
| SCHEMBL11125053 | 0.80 | CYP19A1 (0.66) | CYP19A1MAPTKDM4EALDH1A1THRB | |
| SCHEMBL10985659 | 0.78 | CYP19A1 (0.60) | CYP19A1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL20341079 | 0.76 | CYP19A1 (0.61) | CYP19A1MAPTNPC1CYP3A4RAB9A | |
| SCHEMBL10695151 | 0.76 | CYP19A1 (0.61) | CYP19A1MAPTNPC1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4748185-A | RODENTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-31 | — | — | US | disclosed |
| EP-0098629-B1 | ANTI-COAGULANTS OF THE 4-HYDROXYCOUMARIN TYPE, THE PREPARATION THEREOF, AND RODENTICIDAL COMPOSITIONS (BAITS) COMPRISING SUCH ANTI-COAGULANTS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-08-26 | — | — | EP | disclosed |
| US-4520007-A | Anti-coagulants of the 4-hydroxycoumarin type and rodenticidal compositions (baits) comprising such anti-coagulants | SHELL OIL COMPANY (US) | 1985-05-28 | — | — | US | disclosed |
| EP-0098629-A1 | Anti-coagulants of the 4-hydroxycoumarin type, the preparation thereof, and rodenticidal compositions (baits) comprising such anti-coagulants | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-01-18 | — | — | EP | disclosed |