Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6124100 | 0.82 | CYP19A1 (0.77) | CYP19A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL10692675 | 0.78 | CYP19A1 (0.67) | CYP19A1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL25732123 | 0.78 | CYP19A1 (0.67) | CYP19A1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL25732095 | 0.78 | CYP19A1 (0.67) | CYP19A1MAPTSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL28522066 | 0.78 | CYP19A1 (0.67) | CYP19A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9149487 | 0.78 | HTR2A (0.49) | CYP19A1MAPTSMN1; SMN2CASP3RAB9A | |
| SCHEMBL15256115 | 0.75 | LMNA (0.50) | CYP19A1MAPTSMN1; SMN2CASP3RAB9A | |
| SCHEMBL10815794 | 0.75 | CYP19A1 (0.66) | CYP19A1MAPTSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL10525226 | 0.75 | CYP19A1 (0.61) | CYP19A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10693966 | 0.75 | CYP19A1 (0.61) | CYP19A1MAPTRAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4520007-A | Anti-coagulants of the 4-hydroxycoumarin type and rodenticidal compositions (baits) comprising such anti-coagulants | SHELL OIL COMPANY (US) | 1985-05-28 | — | — | US | disclosed |
| EP-0098629-A1 | Anti-coagulants of the 4-hydroxycoumarin type, the preparation thereof, and rodenticidal compositions (baits) comprising such anti-coagulants | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-01-18 | — | — | EP | disclosed |