Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PIP5K1C | O60331 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694161 | 1.00 | ALDH1A1 (0.37) | ALDH1A1DAORAB9APIP5K1CPIK3CA | |
| SCHEMBL10693292 | 1.00 | ALDH1A1 (0.37) | ALDH1A1DAORAB9APIP5K1CPIK3CA | |
| Hydrochloric Acid SCHEMBL10691286 | 0.99 | ALDH1A1 (0.37) | ALDH1A1DAORAB9APIP5K1CPIK3CA | |
| Hydrochloric Acid SCHEMBL10689372 | 0.99 | ALDH1A1 (0.37) | ALDH1A1DAORAB9APIP5K1CPIK3CA | |
| Hydrochloric Acid SCHEMBL10693675 | 0.99 | ALDH1A1 (0.37) | ALDH1A1DAORAB9APIP5K1CPIK3CA | |
| SCHEMBL10691962 | 0.88 | DAO (0.36) | ALDH1A1DAOROCK2 | |
| SCHEMBL10688638 | 0.88 | DAO (0.36) | ALDH1A1DAOROCK2 | |
| SCHEMBL10693179 | 0.88 | DAO (0.36) | ALDH1A1DAOROCK2 | |
| Hydrochloric Acid SCHEMBL10693082 | 0.87 | DAO (0.35) | ALDH1A1DAOROCK2 | |
| Hydrochloric Acid SCHEMBL10692986 | 0.87 | DAO (0.35) | ALDH1A1DAOROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766142-A | ANTICARCINOGENIC AGENTS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1988-08-23 | — | — | US | disclosed |