Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.68 |
| ▸ | PBK | Q96KB5 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.44 |
| ▸ | CDK2AP1 | O14519 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310476 | 0.82 | MAPK1 (0.46) | MAPK1OPRK1ALDH1A1HPGDMEN1 | |
| Troxipide SCHEMBL400623 | 0.81 | MAPK1 (1.00) | MAPK1OPRK1MEN1KMT2A | |
| SCHEMBL1564166 | 0.79 | CHEK1 (0.67) | CHEK1CDK2AP1 | |
| SCHEMBL1580074 | 0.76 | MAPK1 (0.56) | MAPK1OPRK1PBKALDH1A1HPGD | |
| SCHEMBL13845998 | 0.76 | MAPK1 (0.72) | MAPK1OPRK1CHEK1CDK2AP1MEN1 | |
| SCHEMBL13846013 | 0.76 | MAPK1 (0.72) | MAPK1OPRK1CHEK1CDK2AP1MEN1 | |
| SCHEMBL13881171 | 0.75 | MAPK1 (0.61) | MAPK1OPRK1ALDH1A1DRD4CHEK1 | |
| SCHEMBL10352761 | 0.75 | MAPK1 (0.44) | MAPK1OPRK1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL3591417 | 0.74 | MAPK1 (0.60) | MAPK1OPRK1PBKALDH1A1HPGD | |
| SCHEMBL3591415 | 0.74 | MAPK1 (0.60) | MAPK1OPRK1PBKALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254068-A2 | Novel therapeutic agent for gastritis | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1988-01-27 | — | — | EP | disclosed |