Troxipide

Troxipide

SCHEMBL400623

COc1cc(C(=O)NC2CCCNC2)cc(OC)c1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 1.00
OPRK1 P41145 1/20 1.00
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
PKM P14618 1/20 0.60
POLB P06746 1/20 0.56
TSHR P16473 1/20 0.54
ATM Q13315 1/20 0.53
SIRT5 Q9NXA8 1/20 0.52
TDP1 Q9NUW8 1/20 0.51
MMP2 P08253 3/20 0.50
ANPEP P15144 3/20 0.50
CXCR6 O00574 1/20 0.49
CXCR4 P61073 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31432699 0.85 MAPK1 (0.74) MAPK1OPRK1MEN1KMT2APKM
SCHEMBL463415 0.85 MAPK1 (0.74) MAPK1OPRK1MEN1KMT2APKM
SCHEMBL13845998 0.84 MAPK1 (0.72) MAPK1OPRK1MEN1KMT2A
SCHEMBL13846013 0.84 MAPK1 (0.72) MAPK1OPRK1MEN1KMT2A
SCHEMBL3140700 0.83 POLB (0.77) MAPK1OPRK1MEN1KMT2APKM
SCHEMBL10692729 0.81 MAPK1 (0.68) MAPK1OPRK1MEN1KMT2A
SCHEMBL9205578 0.81 MAPK1 (0.68) MAPK1OPRK1MEN1KMT2APKM
SCHEMBL16789648 0.80 MAPK1 (0.67) MAPK1OPRK1MEN1KMT2APKM
SCHEMBL28324081 0.80 MAPK1 (0.67) MAPK1OPRK1MEN1KMT2APKM
SCHEMBL14748332 0.80 MAPK1 (0.66) MAPK1OPRK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250259704-A1 SYSTEMS AND METHODS FOR CELL-FREE ITERATIVE SITE SATURATION MUTAGENESIS AND ITS APPLICATION FOR THE DIRECTED EVOLUTION OF ENZYMES CATALYZING UNNATURAL REACTIONS U.S. DEPARTMENT OF ENERGY 2025-08-14 US claimed
US-20250129016-A1 PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-04-24 US claimed
CN-119331762-A Bifidobacterium breve BX-18 and application thereof 内蒙古农业大学 2025-01-21 CN claimed
CN-119233997-A Tetrahedral antibodies 生物分子控股有限责任公司 2024-12-31 CN claimed
EP-4463485-A2 TETRAHEDRAL ANTIBODIES Biomolecular Holdings LLC (US) 2024-11-20 EP claimed
CN-118384290-A Hybrid immunoglobulins containing non-peptide linkages 生物分子控股有限责任公司 2024-07-26 CN claimed
EP-4031948-B1 A METHOD AND A DEVICE FOR PICKING AND PLACING ITEMS ABB SCHWEIZ AG (CH) 2024-07-03 EP claimed
WO-2023250524-A1 SYSTEMS AND METHODS FOR CELL-FREE ITERATIVE SITE SATURATION MUTAGENESIS AND ITS APPLICATION FOR THE DIRECTED EVOLUTION OF ENZYMES CATALYZING UNNATURAL REACTIONS NORTHWESTERN UNIVERSITY (US) 2023-12-28 WO claimed
WO-2023137387-A2 TETRAHEDRAL ANTIBODIES BIOMOLECULAR HOLDINGS LLC (US) 2023-07-20 WO claimed
WO-2023137373-A1 TETRAHEDRAL ANTIBODIES BIOMOLECULAR HOLDINGS LLC (US) 2023-07-20 WO claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-5908824-A DISPERSED HOMOGENEOUSLY IN AND ADSORBED HOMOGENEOUSLY ONTO A MUCOSA PROTECTING AND/OR TISSUE REPAIRING AGENT DOTT RESEARCH LABORATORY (JP) 1999-06-01 US claimed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 US claimed
CN-2269254-Y Jet core box for radiator sand core TAIYUAN SCIENT AND EDUCATION C (CN) 1997-12-03 CN claimed
EP-0770390-A1 Nasally administrable compositions containing physiologically active peptides DOTT RESEARCH LABORATORY (JP) 1997-05-02 EP claimed
CN-2234834-Y Rotary coring type core shooter TAIYUAN SCIENCE & EDUCATION CO (CN) 1996-09-11 CN claimed
US-5238946-A Therapeutic agent for gastritis KYORIN SEIYAKU KABUSHIKI KAISHA (JP) 1993-08-24 US claimed
CN-1069808-A Determine the method and apparatus of object height 1993-03-10 CN claimed
EP-0254068-B1 NOVEL THERAPEUTIC AGENT FOR GASTRITIS KYORIN SEIYAKU KABUSHIKI KAISHA (JP) 1992-08-26 EP claimed
EP-0254068-A2 Novel therapeutic agent for gastritis KYORIN SEIYAKU KABUSHIKI KAISHA (JP) 1988-01-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129016-A1 PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF RCC2, PPOX, FTO MAPK1 2762/4885OPRK1 2540/4885MEN1 92/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.