SCHEMBL10692737

SCHEMBL10692737

CCCCCCCCc1ccc(COc2ccc(-c3ncc(CCCC)cn3)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.62
MAPT P10636 4/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
HSD17B10 Q99714 3/20 0.62
KDM4E B2RXH2 2/20 0.62
MEN1 O00255 2/20 0.62
USP2 O75604 2/20 0.62
ALDH1A1 P00352 2/20 0.62
KMT2A Q03164 2/20 0.62
GAA P10253 1/20 0.62
HPGD P15428 1/20 0.62
RARB P10826 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.54
CASP3 P42574 1/20 0.51
SENP8 Q96LD8 1/20 0.51
SENP7 Q9BQF6 1/20 0.51
SENP6 Q9GZR1 1/20 0.51
HRH3 Q9Y5N1 2/20 0.51
NPC1 O15118 4/20 0.50
STAT3 P40763 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10693718 1.00 RAB9A (0.62) RAB9AMAPTSMN1; SMN2HSD17B10KDM4E
SCHEMBL10693363 1.00 RAB9A (0.62) RAB9AMAPTSMN1; SMN2HSD17B10KDM4E
SCHEMBL10694630 1.00 RAB9A (0.62) RAB9AMAPTSMN1; SMN2HSD17B10KDM4E
SCHEMBL10694137 1.00 RAB9A (0.62) RAB9AMAPTSMN1; SMN2HSD17B10KDM4E
SCHEMBL10693474 1.00 RAB9A (0.62) RAB9AMAPTSMN1; SMN2HSD17B10KDM4E
SCHEMBL10694638 1.00 RAB9A (0.62) RAB9AMAPTSMN1; SMN2HSD17B10KDM4E
SCHEMBL10692413 1.00 RAB9A (0.62) RAB9AMAPTSMN1; SMN2HSD17B10KDM4E
SCHEMBL10693209 1.00 RAB9A (0.62) RAB9AMAPTSMN1; SMN2HSD17B10KDM4E
SCHEMBL10694729 1.00 RAB9A (0.62) RAB9AMAPTSMN1; SMN2HSD17B10KDM4E
SCHEMBL9347849 0.99 RAB9A (0.63) RAB9AMAPTSMN1; SMN2HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4776973-A LIQUID CRYSTAL ELECTROOPTICS DISPLAY DEVICE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-10-11 US disclosed