SCHEMBL10692820

SCHEMBL10692820

NCCCOc1cccc(C(F)(F)F)c1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.57
MAOB P27338 3/20 0.56
AOC3 Q16853 1/20 0.56
KDM4E B2RXH2 4/20 0.54
LMNA P02545 2/20 0.50
PKM P14618 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
ALDH1A1 P00352 2/20 0.49
GAA P10253 1/20 0.49
USP2 O75604 1/20 0.49
HTT P42858 1/20 0.49
ALOX15 P16050 1/20 0.48
LTA4H P09960 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8188767 0.95 L3MBTL1 (0.56) L3MBTL1MAOBAOC3KDM4ELMNA
SCHEMBL3524104 0.91 L3MBTL1 (0.59) L3MBTL1MAOBAOC3KDM4ELMNA
SCHEMBL10458221 0.86 L3MBTL1 (0.60) L3MBTL1MAOBAOC3KDM4ELMNA
SCHEMBL9721587 0.84 L3MBTL1 (0.59) L3MBTL1MAOBAOC3KDM4ELMNA
SCHEMBL31096458 0.84 L3MBTL1 (0.59) L3MBTL1MAOBAOC3KDM4ELMNA
SCHEMBL12062140 0.83 L3MBTL1 (0.58) L3MBTL1LMNATAAR1HTT
SCHEMBL2429378 0.83 L3MBTL1 (0.66) L3MBTL1KDM4ELMNAALDH1A1GAA
SCHEMBL3163926 0.83 L3MBTL1 (0.61) L3MBTL1MAOBAOC3KDM4ELMNA
SCHEMBL7199882 0.83 L3MBTL1 (0.57) L3MBTL1MAOBAOC3KDM4ELMNA
SCHEMBL2089594 0.83 L3MBTL1 (0.57) L3MBTL1MAOBAOC3KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2389352-B1 ARGINASE INHIBITORS AND METHODS OF USE UNIV PENNSYLVANIA (US) 2019-05-08 EP disclosed
WO-2015155306-A1 NEW TRPA1 ANTAGONISTS ALMIRALL, S.A. (ES) 2015-10-15 WO disclosed
EP-0252876-A1 Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds CIBA-GEIGY AG (CH) 1988-01-13 EP disclosed
EP-0183147-A2 Beta-substituted aminophenethylazol derivatives NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-06-04 EP disclosed