Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692831 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTHIF1AKMT2ATP53 | |
| SCHEMBL22435456 | 0.88 | ALDH1A1 (0.51) | ALDH1A1MAPTHIF1AKMT2ATP53 | |
| SCHEMBL5569343 | 0.85 | KMT2A (0.49) | ALDH1A1MAPTHIF1AKMT2ATP53 | |
| SCHEMBL9628829 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MAPTHIF1AKMT2ATP53 | |
| SCHEMBL31525966 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTHIF1AKMT2ATP53 | |
| SCHEMBL29325099 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTHIF1AKMT2ATP53 | |
| SCHEMBL18917618 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPTHIF1AKMT2ATP53 | |
| SCHEMBL13141151 | 0.81 | SMN1; SMN2 (0.54) | ALDH1A1MAPTHIF1AKMT2ATP53 | |
| SCHEMBL24452794 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MAPTHIF1AKMT2ATP53 | |
| SCHEMBL29325700 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTHIF1AKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256586-A1 | Process for the preparation of esters of 4-(2,3-epoxypropoxy)phenylacetic acid and 4-(2-hydroxy-3-isopropylamino-propoxy)phenylacetic acid and/or atenolol in stereospecific form | GIST-BROCADES N.V. (NL) | 1988-02-24 | — | — | EP | disclosed |
| EP-0065542-A4 | COMPOUNDS SUITABLE FOR TREATMENT OR PROPHYLAXIS OF CARDIAC DISORDERS. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-04-25 | — | — | EP | disclosed |
| EP-0065542-A1 | COMPOUNDS SUITABLE FOR TREATMENT OR PROPHYLAXIS OF CARDIAC DISORDERS. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1982-12-01 | — | — | EP | disclosed |
| WO-1982001869-A1 | METHOD FOR TREATMENT OR PROPHYLAXIS OF CARDIAC DISORDERS | AMERICAN HOSPITAL SUPPLY CORP (US) | 1982-06-10 | — | — | WO | disclosed |