Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14308370 | 0.79 | CHRM2 (0.47) | ALDH1A1HTTHPGDCHRM2KDM4E | |
| SCHEMBL28354630 | 0.79 | HRAS (0.49) | HRASMAPTGAANPC1RAB9A | |
| SCHEMBL206646 | 0.78 | HRAS (0.65) | HRASKDM4EMAPTNPC1RAB9A | |
| Methyl Alcohol SCHEMBL27462113 | 0.77 | HRAS (0.64) | HRASALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL10776729 | 0.77 | HRAS (0.68) | HRASKDM4EMAPTGAANPC1 | |
| Hydrochloric Acid SCHEMBL6967279 | 0.77 | HRAS (0.62) | HRASKDM4EMAPTGAANPC1 | |
| SCHEMBL10802765 | 0.76 | HRAS (0.58) | HRASALDH1A1HTTHPGDLMNA | |
| SCHEMBL14353230 | 0.76 | MC5R (0.46) | HRASHPGDMAPTKMT2A | |
| SCHEMBL4629342 | 0.75 | CHRM2 (0.50) | ALDH1A1HTTHPGDCHRM2KDM4E | |
| SCHEMBL607175 | 0.73 | HTT (0.67) | ALDH1A1HTTHPGDCHRM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |