SCHEMBL206646

SCHEMBL206646

c1ccc(CNOCc2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HRAS P01112 1/20 0.65
TSHR P16473 1/20 0.50
BCHE P06276 3/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
IDO1 P14902 3/20 0.46
THRB P10828 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CYP3A4 P08684 2/20 0.44
MAPT P10636 2/20 0.44
AGXT P21549 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ADH1B P00325 1/20 0.41
ADH1C P00326 1/20 0.41
ADH1A P07327 1/20 0.41
ADH7 P40394 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10776729 0.98 HRAS (0.68) HRASTSHRBCHENPC1RAB9A
Hydrochloric Acid SCHEMBL6967279 0.98 HRAS (0.62) HRASTSHRBCHENPC1RAB9A
SCHEMBL8339266 0.88 HRAS (0.54) HRASTSHRBCHENPC1RAB9A
SCHEMBL10802765 0.88 HRAS (0.58) HRASBCHENPC1RAB9AMEN1
SCHEMBL8624741 0.84 MAOB (0.57) HRASTSHRBCHENPC1RAB9A
SCHEMBL19853459 0.81 MEN1 (0.65) HRASBCHEMEN1KMT2ATDP1
SCHEMBL14353079 0.81 HRAS (0.64) HRASBCHEIDO1KMT2A
Hydrochloric Acid SCHEMBL6648934 0.80 MRGPRX1 (0.58) HRASKMT2A
SCHEMBL6880235 0.80 HRAS (0.62) HRASTSHRNPC1RAB9AIDO1
SCHEMBL3930158 0.79 HRAS (0.49) HRASTSHRBCHENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250205195-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION AMTIXBIO CO., LTD. (KR) 2025-06-26 US claimed
US-20250034084-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MYCOSIS AMTIXBIO CO., LTD. (KR) 2025-01-30 US claimed
US-20250034083-A1 METHODS FOR PREPARING BENZYLOXYBENZYLAMINE AMINO ACID DERIVATIVES AMTIXBIO CO., LTD. (KR) 2025-01-30 US claimed
US-20250034082-A1 FUNCTIONAL DERIVATIVE COMPOUNDS OF ALANINE AND PROLINE AMINO ACIDS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AMTIXBIO CO., LTD. (KR) 2025-01-30 US claimed
EP-4349329-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION Amtixbio Co., Ltd. (KR) 2024-04-10 EP claimed
CN-110325509-B Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same 阿米蒂比奥有限公司 2024-02-02 CN claimed
CN-116836083-A Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same 阿米蒂比奥有限公司 2023-10-03 CN claimed
WO-2022255801-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION (주)앰틱스바이오 2022-12-08 WO claimed
US-20200199065-A1 FUNCTIONAL DERIVATIVE COMPOUNDS OF ALANINE AND PROLINE AMINO ACIDS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AMTIXBIO CO., LTD. (KR) 2020-06-25 US claimed
CN-110325509-A Functional derivative compound of alanine and proline amino acid and pharmaceutical composition containing same 阿米蒂比奥有限公司 2019-10-11 CN claimed
US-20030149034-A1 INDAZOLES SUBSTITUTED WITH1,1-DIOXOISOTHIAZOLIDINE USEFUL AS INHIBITORS OF CELL PROLIFERATION LG LIFE SCIENCES LTD. (KR) 2003-08-07 US claimed
CN-1432015-A Indazoles substituted with 1, 1-dioxoisothiazolidine useful as cell proliferation inhibitors LG CHEM INVESTMENT LTD (KR) 2003-07-23 CN claimed
EP-1280802-A4 INDAZOLES SUBSTITUTED WITH 1,1-DIOXOISOTHIAZOLIDINE USEFUL AS INHIBITORS OF CELL PROLIFERATION LG LIFE SCIENCES LTD (KR) 2003-06-11 EP claimed
EP-1280802-A1 INDAZOLES SUBSTITUTED WITH 1,1-DIOXOISOTHIAZOLIDINE USEFUL AS INHIBITORS OF CELL PROLIFERATION LG Life Sciences Ltd. (KR) 2003-02-05 EP claimed
WO-2001085726-A1 INDAZOLES SUBSTITUTED WITH 1,1-DIOXOISOTHIAZOLIDINE USEFUL AS INHIBITORS OF CELL PROLIFERATION LG LIFE SCIENCES LTD. (KR) 2001-11-15 WO claimed
EP-0763012-B1 SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS BRITISH BIOTECH PHARM (GB) 1999-06-09 EP claimed
CN-1114106-A Benzylamine derivatives OTSUKA PHARMA CO LTD (JP) 1995-12-27 CN claimed
EP-0666840-A1 BENZYLAMINE DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-08-16 EP claimed
WO-1995006630-A1 BENZYLAMINE DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-03-09 WO claimed
US-4696964-A HEAT RESISTANCE, OXIDATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1987-09-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034083-A1 METHODS FOR PREPARING BENZYLOXYBENZYLAMINE AMINO ACID DERIVATIVES BCAT2, BCAT1, DAO HRAS 4309/4885TSHR 4831/4885BCHE 90/4885
US-20250034082-A1 FUNCTIONAL DERIVATIVE COMPOUNDS OF ALANINE AND PROLINE AMINO ACIDS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME PEPD, BCAT1, ANPEP HRAS 3485/4885TSHR 4818/4885BCHE 902/4885
US-20200199065-A1 FUNCTIONAL DERIVATIVE COMPOUNDS OF ALANINE AND PROLINE AMINO ACIDS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME PEPD, BCAT1, ANPEP HRAS 3485/4885TSHR 4818/4885BCHE 902/4885
US-20030149034-A1 INDAZOLES SUBSTITUTED WITH1,1-DIOXOISOTHIAZOLIDINE USEFUL AS INHIBITORS OF CELL PROLIFERATION CCNA1, CCNI, CCNT1 HRAS 2718/4885TSHR 4025/4885BCHE 4766/4885
US-20250034084-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MYCOSIS ERG28, BCAT2, AADAT HRAS 3909/4885TSHR 4858/4885BCHE 565/4885
US-20250205195-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION TSLP, IL2RA, TRPC7 HRAS 1533/4885TSHR 1160/4885BCHE 1012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.