Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.69 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 2/20 | 0.45 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10762411 | 0.93 | ALDH1A1 (0.69) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10692692 | 0.91 | KCNH2 (0.65) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10530714 | 0.91 | ALDH1A1 (0.70) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL10529374 | 0.89 | ALDH1A1 (0.70) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL5571239 | 0.89 | ALDH1A1 (0.78) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL10530738 | 0.88 | ALDH1A1 (0.77) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9733802 | 0.88 | ALDH1A1 (0.76) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL6489034 | 0.88 | ALDH1A1 (0.76) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9734892 | 0.88 | ALDH1A1 (0.76) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10764195 | 0.84 | KCNH2 (0.63) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791118-A | BACTERICIDES; GRAMNEGATIVE AND -POSITIVE BACTERIA; ANIMAL INFECTIONS; PLANT DISEASES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1988-12-13 | — | — | US | claimed |
| US-4791118-A | BACTERICIDES; GRAMNEGATIVE AND -POSITIVE BACTERIA; ANIMAL INFECTIONS; PLANT DISEASES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1988-12-13 | — | — | US | disclosed |
| EP-0216323-A2 | Quinolonecarboxylic acid derivatives and their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-04-01 | — | — | EP | disclosed |