Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51008 | 0.91 | LMNA (0.61) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL30330977 | 0.90 | LMNA (0.59) | LMNAMEN1KMT2APOLBALDH1A1 | |
| Bromide SCHEMBL27972711 | 0.90 | LMNA (0.59) | LMNAMEN1KMT2APOLBALDH1A1 | |
| Naphthalene SCHEMBL9683208 | 0.90 | LMNA (0.59) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4456358 | 0.86 | LMNA (0.51) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL30726741 | 0.86 | LMNA (0.51) | LMNAMEN1KMT2APOLBALDH1A1 | |
| Carbazole SCHEMBL29134578 | 0.83 | LMNA (0.53) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL645551 | 0.83 | LMNA (0.58) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL29359863 | 0.83 | LMNA (0.58) | LMNAMEN1KMT2APOLBALDH1A1 | |
| Benzimidazole SCHEMBL8417549 | 0.82 | LMNA (0.51) | LMNAMEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792508-A | STEREOISOMERIC NAPHTHALENE IMIDAZOLE PERYLENES, ARYL AMINES | XEROX CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |