Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.71 |
| ▸ | NQO1 | P15559 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688883 | 1.00 | VKORC1 (0.71) | VKORC1NQO1PTPN1MAOBKDM4E | |
| SCHEMBL10694018 | 0.94 | VKORC1 (0.82) | VKORC1NQO1PTPN1MAOBKDM4E | |
| SCHEMBL10692706 | 0.94 | VKORC1 (0.82) | VKORC1NQO1PTPN1MAOBKDM4E | |
| SCHEMBL10691535 | 0.93 | VKORC1 (0.67) | VKORC1NQO1PTPN1MAOBKDM4E | |
| SCHEMBL10691142 | 0.92 | VKORC1 (0.65) | VKORC1NQO1PTPN1MAOBKDM4E | |
| SCHEMBL10690242 | 0.90 | VKORC1 (0.78) | VKORC1NQO1MAOBKDM4EALDH1A1 | |
| SCHEMBL10687567 | 0.90 | VKORC1 (0.78) | VKORC1NQO1ALDH1A1PRNPRXFP1 | |
| SCHEMBL10866030 | 0.90 | VKORC1 (0.62) | VKORC1NQO1PTPN1MAOBKDM4E | |
| SCHEMBL10605191 | 0.90 | VKORC1 (0.62) | VKORC1NQO1MAOBKDM4EALDH1A1 | |
| SCHEMBL20530982 | 0.90 | VKORC1 (0.62) | VKORC1NQO1MAOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4748185-A | RODENTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-31 | — | — | US | disclosed |