Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 17/20 | 0.64 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289278 | 0.88 | KDM4E (0.65) | P2RX7CAPN1KDM4EALDH1A1 | |
| SCHEMBL1612567 | 0.88 | KDM4E (0.65) | P2RX7CAPN1KDM4EALDH1A1 | |
| SCHEMBL288664 | 0.86 | P2RX7 (0.61) | P2RX7CAPN1KDM4EALDH1A1 | |
| SCHEMBL289740 | 0.86 | P2RX7 (0.61) | P2RX7CAPN1KDM4EALDH1A1 | |
| SCHEMBL24434796 | 0.78 | KMT2A (0.57) | P2RX7CAPN1ALDH1A1 | |
| SCHEMBL927807 | 0.78 | KMT2A (0.57) | P2RX7CAPN1ALDH1A1 | |
| SCHEMBL2583749 | 0.78 | KMT2A (0.57) | P2RX7CAPN1ALDH1A1 | |
| SCHEMBL2581865 | 0.78 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2581860 | 0.78 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL30158884 | 0.77 | P2RX7 (0.54) | P2RX7CAPN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4742061-A | Benzoc[c]-1,5-naphthyridines and related compounds as memory enhancing agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-05-03 | — | — | US | disclosed |