Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.76 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898907 | 0.87 | ADRB2 (0.77) | ADRB2ADRB1 | |
| SCHEMBL7902030 | 0.87 | ADRB2 (0.77) | ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL7900096 | 0.86 | ADRB2 (0.75) | ADRB2ADRB1 | |
| SCHEMBL11196087 | 0.83 | ADRB2 (0.75) | ADRB2ADRB1LMNAADRB3HTR1A | |
| SCHEMBL11868102 | 0.83 | ADRB2 (0.82) | ADRB2ADRB1LMNAADRB3HTR1A | |
| Hydrochloric Acid SCHEMBL11874444 | 0.81 | ADRB2 (0.80) | ADRB2ADRB1LMNAADRB3HTR1A | |
| SCHEMBL28179814 | 0.81 | ADRB2 (0.80) | ADRB2ADRB1LMNAADRB3HTR1A | |
| SCHEMBL30666392 | 0.81 | ADRB2 (0.80) | ADRB2ADRB1LMNAADRB3HTR1A | |
| SCHEMBL11195953 | 0.81 | ADRB2 (0.71) | ADRB2ADRB1LMNAADRB3HTR1A | |
| Oxalic Acid SCHEMBL10917468 | 0.81 | ADRB2 (0.71) | ADRB2ADRB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256586-A1 | Process for the preparation of esters of 4-(2,3-epoxypropoxy)phenylacetic acid and 4-(2-hydroxy-3-isopropylamino-propoxy)phenylacetic acid and/or atenolol in stereospecific form | GIST-BROCADES N.V. (NL) | 1988-02-24 | — | — | EP | claimed |