Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.50 |
| ▸ | CNR2 | P34972 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412903 | 1.00 | TLR8 (0.50) | TLR8CNR2TP53OXER1MAPT | |
| SCHEMBL8426489 | 1.00 | TLR8 (0.50) | TLR8CNR2TP53OXER1MAPT | |
| SCHEMBL21278119 | 0.98 | TLR8 (0.49) | TLR8CNR2TP53OXER1CNR1 | |
| SCHEMBL10413631 | 0.89 | TLR8 (0.49) | TLR8CNR2TP53OXER1 | |
| SCHEMBL3847993 | 0.87 | OXER1 (0.51) | TLR8CNR2TP53OXER1CNR1 | |
| SCHEMBL6211295 | 0.86 | CNR2 (0.47) | TLR8CNR2TP53OXER1CNR1 | |
| SCHEMBL10413247 | 0.82 | MEN1 (0.56) | TLR8CNR2TP53MAPTSMN1; SMN2 | |
| SCHEMBL11153101 | 0.82 | MEN1 (0.56) | TLR8CNR2TP53MAPTSMN1; SMN2 | |
| SCHEMBL11607923 | 0.82 | MEN1 (0.56) | TLR8CNR2TP53MAPTSMN1; SMN2 | |
| SCHEMBL4212491 | 0.82 | MEN1 (0.56) | TLR8CNR2TP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |