SCHEMBL3847993

SCHEMBL3847993

CCCCCc1cc2ccccc2n1CCCCC

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OXER1 Q8TDS5 9/20 0.51
TLR8 Q9NR97 4/20 0.48
AGTR1 P30556 1/20 0.47
AGTR2 P50052 1/20 0.47
CNR2 P34972 5/20 0.45
TP53 P04637 1/20 0.45
CNR1 P21554 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10413631 0.92 TLR8 (0.49) OXER1TLR8AGTR1AGTR2CNR2
SCHEMBL28047369 0.92 AGTR1 (0.51) OXER1TLR8AGTR1AGTR2
SCHEMBL21278119 0.89 TLR8 (0.49) OXER1TLR8CNR2TP53CNR1
SCHEMBL10412903 0.87 TLR8 (0.50) OXER1TLR8CNR2TP53CNR1
SCHEMBL8426489 0.87 TLR8 (0.50) OXER1TLR8CNR2TP53CNR1
SCHEMBL10693099 0.87 TLR8 (0.50) OXER1TLR8CNR2TP53CNR1
SCHEMBL6211295 0.86 CNR2 (0.47) OXER1TLR8AGTR1AGTR2CNR2
SCHEMBL287205 0.85 OXER1 (0.69) OXER1AGTR1AGTR2
SCHEMBL28223276 0.83 OXER1 (0.53) OXER1
SCHEMBL24026931 0.83 OXER1 (0.50) OXER1TLR8AGTR1AGTR2CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1195641-B1 Film/Screen system and image-forming system for use in direct X-ray applications AGFA GEVAERT (BE) 2004-12-29 EP claimed
US-6528227-B2 Radiation-sensitive black-and-white silver halide photographic material in contact with screen sheets designed to emit electrons when exposed to X-rays with an energy greater than or equal to 10 kVp; radiology AGFA-GEVAERT (BE) 2003-03-04 US claimed
US-20020076640-A1 Film/screen system and image-forming system for use in direct X-ray applications AGFA-GEVAERT (BE) 2002-06-20 US claimed
EP-1195641-A1 Film/Screen system and image-forming system for use in direct X-ray applications Agfa-Gevaert (BE) 2002-04-10 EP claimed
EP-0915848-A1 1,2-DIARYLINDOLE AS COX-2 INHIBITORS LABORATOIRES UPSA (FR) 1999-05-19 EP claimed
US-5723485-A ANALGESIC, ANTIINFLAMMATORY AGENTS LABORATORIES UPSA (FR) 1998-03-03 US claimed
WO-1998005639-A1 1,2-DIARYLINDOLE AS COX-2 INHIBITORS LABORATOIRES UPSA (FR) 1998-02-12 WO claimed
CN-109678788-B 1, 2-diaryl indole, derivative and synthetic method thereof 湘潭大学 2021-05-04 CN disclosed
EP-2101736-A2 HOMOGENEOUS PASTE AND GEL FORMULATIONS Merial Limited (US) 2009-09-23 EP disclosed
WO-2008077130-A2 HOMOGENEOUS PASTE AND GEL FORMULATIONS MERIAL LIMITED (US) 2008-06-26 WO disclosed
US-20080039625-A1 Screening Methods LAUTENS MARK 2008-02-14 US disclosed
US-20080027011-A1 Homogeneous paste and gel formulations MERIAL LIMITED 2008-01-31 US disclosed
WO-2007129169-A2 COX- II INHIBITORS FOR IMPROVING REPRODUCTIVE SUCCESS IN A FEMALE ANIMAL PFIZER LIMITED (GB) 2007-11-15 WO disclosed
US-4387154-A SPACED MICROVESSELS HAVING A SURFACE OPENING FILLED WITH PHOTOSENSITI MATERIAL; ANTIHALATION AGENTS; SUPPRESSION OF IMAGE SPREADING; X-RAY COLOR; BLACK AND WHITE FILMS EASTMAN KODAK COMPANY (US) 1983-06-07 US disclosed
US-4387146-A MICROVESSELS, PATTERNS EASTMAN KODAK COMPANY (US) 1983-06-07 US disclosed
US-4375507-A Imaging with nonplanar support multicolor filter elements EASTMAN KODAK COMPANY (US) 1983-03-01 US disclosed
US-4362806-A PHOTOGRAPHY, SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1982-12-07 US disclosed
US-4269914-A INCLUDING A LAYER TO RECEIVE AND IMMOBILIZE A DIFFUSIBLE DESENSITIZER ABLE TO EFFECT THE SENSITIVITY OF A SILVER HALIDE EMULSION TO ELECTROMAGNETIC RADIATION AND A BARRIER LAYER EASTMAN KODAK COMPANY (US) 1981-05-26 US disclosed
EP-0018268-A2 Ultrasonographic elements containing multiple layers and process for preparing images EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-10-29 EP disclosed
US-4223082-A ELECTROMAGNETIC WAVES EASTMAN KODAK COMPANY (US) 1980-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027011-A1 Homogeneous paste and gel formulations EPX, CAT, PEF1 OXER1 2797/4885TLR8 2645/4885AGTR1 4570/4885
US-20080039625-A1 Screening Methods CBR3, ZKSCAN2, CRBN OXER1 168/4885TLR8 2723/4885AGTR1 609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.