Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 6/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.44 |
| ▸ | CTSB | P07858 | 4/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693230 | 1.00 | ACE (0.48) | ACEPPARGPPARAMMECPA1 | |
| SCHEMBL14021649 | 0.85 | ITGB3 (0.55) | ACEPPARGPPARAPTPN1SCN9A | |
| SCHEMBL4889870 | 0.85 | ITGB3 (0.55) | ACEPPARGPPARAPTPN1SCN9A | |
| SCHEMBL4889863 | 0.85 | ITGB3 (0.55) | ACEPPARGPPARAPTPN1SCN9A | |
| SCHEMBL7273147 | 0.84 | ACE (0.65) | ACEPPARGPPARAMMECPA1 | |
| SCHEMBL7273142 | 0.84 | ACE (0.65) | ACEPPARGPPARAMMECPA1 | |
| Hydrochloric Acid SCHEMBL7544916 | 0.83 | F10 (0.46) | ACEPPARGMMECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL7544909 | 0.83 | F10 (0.46) | ACEPPARGMMECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL7547543 | 0.82 | FFAR1 (0.48) | ACEPPARGPPARAMMECPA1 | |
| Hydrochloric Acid SCHEMBL7547540 | 0.82 | FFAR1 (0.48) | ACEPPARGPPARAMMECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284632-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1988-10-05 | — | — | EP | disclosed |