Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694335 | 0.92 | ATM (0.38) | HTTKMT2APOLBATMALDH1A1 | |
| SCHEMBL10693715 | 0.92 | ATM (0.38) | HTTKMT2APOLBATMALDH1A1 | |
| SCHEMBL10690275 | 0.92 | ATM (0.38) | HTTKMT2APOLBATMALDH1A1 | |
| SCHEMBL10472874 | 0.76 | CREBBP (0.40) | HTTKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL4490919 | 0.76 | ALDH1A1 (0.54) | HTTKMT2AALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL8640299 | 0.75 | ATM (0.37) | HTTKMT2AATMALDH1A1MEN1 | |
| SCHEMBL3936910 | 0.74 | BCHE (0.50) | HTTPOLBALDH1A1BCHEACHE | |
| Hydrochloric Acid SCHEMBL10690256 | 0.74 | ATM (0.36) | ATML3MBTL1 | |
| Hydrochloric Acid SCHEMBL10693525 | 0.74 | ATM (0.36) | ATML3MBTL1 | |
| SCHEMBL4559778 | 0.69 | CSF1R (0.36) | HTTKMT2APOLBATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766142-A | ANTICARCINOGENIC AGENTS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1988-08-23 | — | — | US | disclosed |