Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HTR1B | P28222 | 8/20 | 0.53 |
| ▸ | HTR1A | P08908 | 7/20 | 0.53 |
| ▸ | HTR2A | P28223 | 4/20 | 0.53 |
| ▸ | HTR2C | P28335 | 3/20 | 0.53 |
| ▸ | HTR7 | P34969 | 3/20 | 0.53 |
| ▸ | HTR5A | P47898 | 3/20 | 0.53 |
| ▸ | HTR2B | P41595 | 3/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10693498 | 1.00 | KMT2A (0.58) | KMT2AHTR1BHTR1AHTR2AHTR2C | |
| Oxalic Acid SCHEMBL10691194 | 0.90 | KMT2A (0.59) | KMT2AHTR1BHTR1AHTR2AHTR2C | |
| Oxalic Acid SCHEMBL10691201 | 0.90 | KMT2A (0.59) | KMT2AHTR1BHTR1AHTR2AHTR2C | |
| Oxalic Acid SCHEMBL10693415 | 0.85 | KMT2A (0.53) | KMT2AHTR1BHTR1AHTR2AHTR2C | |
| Oxalic Acid SCHEMBL10693334 | 0.82 | KMT2A (0.50) | KMT2AHTR1BHTR1AHTR2AHTR2C | |
| Oxalic Acid SCHEMBL10693343 | 0.82 | KMT2A (0.50) | KMT2AHTR1BHTR1AHTR2AHTR2C | |
| Oxalic Acid SCHEMBL10691866 | 0.82 | HTR1D (0.59) | KMT2AHTR1BHTR1AHTR2AHTR2C | |
| Oxalic Acid SCHEMBL10691857 | 0.82 | HTR1D (0.59) | KMT2AHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL10690040 | 0.81 | HTR6 (0.63) | KMT2AHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL10690033 | 0.81 | HTR6 (0.63) | KMT2AHTR1BHTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785016-A | VASOCONSTRICTION, MIGRAINES ALKANEAMINO, ALKANE SULFONAMIDE INDOLES | GLAXO GROUP LIMITED (GB) | 1988-11-15 | — | — | US | disclosed |