Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693751 | 0.84 | ATP4A (0.44) | RAB9ASMN1; SMN2KDM4ECYP1A2CYP2A6 | |
| SCHEMBL10690375 | 0.82 | CYP1A2 (0.34) | RAB9ASMN1; SMN2PDE10ACYP1A2CYP2A6 | |
| SCHEMBL10694506 | 0.82 | ATP4A (0.48) | RAB9ASMN1; SMN2CYP1A2CYP2A6KLKB1 | |
| SCHEMBL10691237 | 0.82 | SMN1; SMN2 (0.36) | RAB9ASMN1; SMN2KDM4EHTTCYP1A2 | |
| SCHEMBL10691659 | 0.81 | MAPT (0.50) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| Iodide SCHEMBL10692587 | 0.81 | CYP1A2 (0.33) | RAB9ASMN1; SMN2PDE10ACYP1A2CYP2A6 | |
| SCHEMBL10687438 | 0.80 | MAPK1 (0.39) | RAB9ASMN1; SMN2KLKB1MAP4K1HCRTR1 | |
| SCHEMBL10689158 | 0.80 | MAPT (0.34) | RAB9ASMN1; SMN2PDE10ACYP1A2CYP2A6 | |
| SCHEMBL10688978 | 0.80 | SMN1; SMN2 (0.34) | RAB9ASMN1; SMN2KDM4ECYP1A2CYP2A6 | |
| SCHEMBL10692769 | 0.80 | MAPK1 (0.39) | RAB9ASMN1; SMN2KDM4EPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738967-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4686227-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-11 | — | — | US | disclosed |
| EP-0165545-A2 | Imidazoisoquinoline compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |