SCHEMBL10693516

SCHEMBL10693516

C=COC.C=Cc1cccc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.42
SIRT1 Q96EB6 1/20 0.42
CHAT P28329 4/20 0.41
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
KDM4E B2RXH2 1/20 0.40
RXRA P19793 1/20 0.40
ACHE P22303 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP2A6 P11509 1/20 0.39
F2 P00734 1/20 0.39
LMNA P02545 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29357296 0.88 SIRT2 (0.50) SIRT2SIRT1CHATMTNR1AMTNR1B
SCHEMBL6863260 0.88 SIRT2 (0.50) SIRT2SIRT1CHATMTNR1AMTNR1B
SCHEMBL14912 0.88 SIRT2 (0.50) SIRT2SIRT1CHATMTNR1AMTNR1B
SCHEMBL31610342 0.88 SIRT2 (0.50) SIRT2SIRT1CHATMTNR1AMTNR1B
Methyl Alcohol SCHEMBL1324478 0.86 MTNR1A (0.47) SIRT2SIRT1CHATMTNR1AMTNR1B
Ammonia Solution, Strong SCHEMBL1824430 0.86 SIRT2 (0.49) SIRT2SIRT1CHATMTNR1AMTNR1B
SCHEMBL30925393 0.86 SIRT2 (0.49) SIRT2SIRT1CHATMTNR1AMTNR1B
SCHEMBL18141098 0.86 SIRT2 (0.49) SIRT2SIRT1CHATMTNR1AMTNR1B
SCHEMBL18139227 0.86 SIRT2 (0.49) SIRT2SIRT1CHATMTNR1AMTNR1B
Potassium SCHEMBL18141101 0.86 SIRT2 (0.49) SIRT2SIRT1CHATMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107109015-A Poly- methallyl alcohol resin combination and its formed body is used 株式会社可乐丽 2017-08-29 CN disclosed
CN-107108779-A Polymethacrylol copolymer, molded article using same, and method for producing polymethacrylol copolymer 株式会社可乐丽 2017-08-29 CN disclosed
CN-107001756-A Polymethallyl alcohol resin composition and molded article using same 株式会社可乐丽 2017-08-01 CN disclosed
EP-0256500-A2 Emulsion polymers containing acrylonitrile or vinylidene chloride THE GLIDDEN COMPANY (US) 1988-02-24 EP disclosed