Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.55 |
| ▸ | MGLL | Q99685 | 3/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692700 | 1.00 | THRA (0.64) | THRATHRBSMPD1MGLLS1PR2 | |
| SCHEMBL17230968 | 1.00 | THRA (0.64) | THRATHRBSMPD1MGLLS1PR2 | |
| SCHEMBL14926443 | 1.00 | THRA (0.64) | THRATHRBSMPD1MGLLS1PR2 | |
| SCHEMBL14926440 | 0.99 | THRA (0.62) | THRATHRBSMPD1MGLLS1PR2 | |
| SCHEMBL15295180 | 0.90 | PDE4D (0.53) | THRATHRBMGLLHPGD | |
| SCHEMBL9641090 | 0.90 | PTPN11 (0.57) | THRATHRBSMPD1MGLLS1PR2 | |
| SCHEMBL9437150 | 0.87 | THRA (0.68) | THRATHRBALDH1A1HPGDPLA2G2D | |
| SCHEMBL15731804 | 0.87 | THRA (0.68) | THRATHRBALDH1A1HPGDPLA2G2D | |
| SCHEMBL9440043 | 0.87 | THRA (0.68) | THRATHRBALDH1A1HPGDPLA2G2D | |
| SCHEMBL9440284 | 0.87 | THRA (0.68) | THRATHRBALDH1A1HPGDPLA2G2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256303-A2 | Liquid crystal compounds having fluorine-containing core | POLAROID CORPORATION (US) | 1988-02-24 | — | — | EP | disclosed |