Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CEL | P19835 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12290554 | 0.93 | SMN1; SMN2 (0.48) | SMN1; SMN2OPRL1NPSR1GLAHTT | |
| SCHEMBL10387633 | 0.87 | OPRL1 (0.49) | SMN1; SMN2OPRL1NPSR1GLAHTT | |
| SCHEMBL3796466 | 0.87 | CEL (0.44) | SMN1; SMN2OPRL1NPSR1GLAHTT | |
| SCHEMBL15994822 | 0.86 | TSHR (0.43) | SMN1; SMN2OPRL1NPSR1GLAHTT | |
| SCHEMBL4689694 | 0.86 | OPRL1 (0.61) | SMN1; SMN2OPRL1GRM2TP53ABCB1 | |
| SCHEMBL3791245 | 0.86 | TSHR (0.41) | SMN1; SMN2OPRL1NPSR1GLAHTT | |
| Cyclopropane SCHEMBL28426089 | 0.86 | HTR2A (0.46) | SMN1; SMN2OPRL1NPSR1GLAHTT | |
| SCHEMBL3791971 | 0.85 | CEL (0.43) | SMN1; SMN2OPRL1NPSR1GLAHTT | |
| SCHEMBL20606723 | 0.83 | OPRL1 (0.60) | SMN1; SMN2OPRL1TP53ABCB1MEN1 | |
| SCHEMBL11751246 | 0.83 | TSHR (0.45) | SMN1; SMN2OPRL1NPSR1GLAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266662-A2 | Process for the preparation of poly(arylensulphides) with lower crystallization temperature | BAYER AG (DE) | 1988-05-11 | — | — | EP | disclosed |