Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726560 | 0.82 | PTPN1 (0.40) | PTPN1ERCC5FEN1TSHRSMN1; SMN2 | |
| SCHEMBL30781525 | 0.82 | PTPN1 (0.40) | PTPN1ERCC5FEN1TSHRSMN1; SMN2 | |
| SCHEMBL27850334 | 0.78 | ALDH1A1 (0.41) | TSHRHSD17B10SMN1; SMN2L3MBTL4HPGD | |
| SCHEMBL10515545 | 0.78 | PTPN1 (0.35) | PTPN1ERCC5FEN1KEAP1NFE2L2 | |
| SCHEMBL500029 | 0.77 | SMN1; SMN2 (0.50) | PTPN1TSHRHSD17B10SMN1; SMN2KEAP1 | |
| SCHEMBL9226589 | 0.77 | POLB (0.50) | ERCC5FEN1TSHRSMN1; SMN2HPGD | |
| Butane SCHEMBL10841930 | 0.76 | PTPN1 (0.36) | PTPN1ERCC5FEN1TSHRHSD17B10 | |
| SCHEMBL22395416 | 0.74 | ALDH1A1 (0.40) | KMT2APOLBAPEX1DGAT1 | |
| SCHEMBL1187294 | 0.74 | PTPN1 (0.38) | PTPN1ERCC5FEN1SMN1; SMN2KEAP1 | |
| SCHEMBL30194898 | 0.74 | PTPN1 (0.38) | PTPN1ERCC5FEN1SMN1; SMN2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4786649-A | ANTISEPTICS | OTSUKA PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-11-22 | — | — | US | disclosed |
| US-4684648-A | Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds and compositions thereof | OTSUKA PHARMACEUTICAL COMPANY LIMITED (JP) | 1987-08-04 | — | — | US | disclosed |
| EP-0228035-A2 | Antimicrobial 1-thienyl-4-oxoquinoline-3-carboxylix acid compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-07-08 | — | — | EP | disclosed |
| EP-0181521-A1 | Antimicrobial 1-substituted Phenyl-4-oxoquinoline-3-carboxylic acid compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-21 | — | — | EP | disclosed |