Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394198 | 0.87 | GABRA1 (0.42) | GABRA1GABRB2ALDH1A1KDM4EAKR1B1 | |
| SCHEMBL2162474 | 0.83 | GABRA1 (0.42) | GABRA1GABRB2ALDH1A1KDM4ESLC6A2 | |
| SCHEMBL10561343 | 0.83 | GABRA1 (0.42) | GABRA1GABRB2ALDH1A1KDM4EAKR1B1 | |
| SCHEMBL173732 | 0.83 | GABRA1 (0.42) | GABRA1GABRB2ALDH1A1KDM4EAKR1B1 | |
| SCHEMBL3063776 | 0.83 | GABRA1 (0.42) | GABRA1GABRB2ALDH1A1KDM4EAKR1B1 | |
| SCHEMBL3987139 | 0.81 | GABRA1 (0.41) | GABRA1GABRB2ALDH1A1KDM4EAKR1B1 | |
| SCHEMBL173300 | 0.80 | GABRA1 (0.56) | GABRA1GABRB2ALDH1A1KDM4EAKR1B1 | |
| SCHEMBL29763626 | 0.80 | GABRA1 (0.56) | GABRA1GABRB2ALDH1A1KDM4EAKR1B1 | |
| SCHEMBL27677916 | 0.78 | NPC1 (0.46) | GABRA1GABRB2ALDH1A1KDM4ELMNA | |
| SCHEMBL19437729 | 0.78 | GABRA1 (0.54) | GABRA1GABRB2ALDH1A1KDM4EAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272425-A2 | Resin blends exhibiting improved impact properties | GENERAL ELECTRIC COMPANY (US) | 1988-06-29 | — | — | EP | disclosed |
| EP-0269861-A2 | Impact modified aromatic carbonate compositions | GENERAL ELECTRIC COMPANY (US) | 1988-06-08 | — | — | EP | disclosed |