SCHEMBL10693710

SCHEMBL10693710

COc1ccc(C(OC(C(=O)c2ccccc2)[C@H]2O[C@@H](n3ccc(N)nc3=O)[C@H](OC)[C@@H]2OP(N)O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ST6GAL1 P15907 5/20 0.38
GAPDH P04406 1/20 0.32
NT5E P21589 1/20 0.32
TYMP P19971 1/20 0.31
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31
MTOR P42345 1/20 0.31
MDM2 Q00987 1/20 0.31
NCOA1 Q15788 1/20 0.31
NCOA3 Q9Y6Q9 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4458009 0.89 ST6GAL1 (0.42) ST6GAL1NT5ETYMPLMNATHRB
SCHEMBL17599856 0.83 ST6GAL1 (0.42) ST6GAL1NT5ETYMPLMNATHRB
SCHEMBL6835020 0.83 ST6GAL1 (0.43) ST6GAL1NT5ETYMPLMNATHRB
SCHEMBL6362953 0.80 ST6GAL1 (0.39) ST6GAL1NT5ETYMPLMNATHRB
SCHEMBL7079293 0.80 ST6GAL1 (0.38) ST6GAL1NT5ETYMPLMNATHRB
SCHEMBL6234928 0.79 ST6GAL1 (0.35) ST6GAL1
SCHEMBL5982374 0.79 ST6GAL1 (0.40) ST6GAL1NT5ETYMPLMNATHRB
SCHEMBL5200171 0.79 POLB (0.40) ST6GAL1TYMPLMNATHRBMTOR
SCHEMBL7261574 0.78 ST6GAL1 (0.42) ST6GAL1NT5ETYMPLMNATHRB
SCHEMBL5200194 0.78 POLB (0.37) ST6GAL1NT5ETYMPLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0260032-A2 Compounds for the cleavage at a specific position of RNA, oligomers employed for the formation of said compounds, and starting materials for the synthesis of said oligomers AJINOMOTO CO., INC. (JP) 1988-03-16 EP disclosed