Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST6GAL1 | P15907 | 7/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835020 | 0.92 | ST6GAL1 (0.43) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL17599856 | 0.91 | ST6GAL1 (0.42) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL10693710 | 0.89 | ST6GAL1 (0.38) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL7079293 | 0.89 | ST6GAL1 (0.38) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL6362953 | 0.89 | ST6GAL1 (0.39) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL5982374 | 0.86 | ST6GAL1 (0.40) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL1318619 | 0.85 | NT5E (0.45) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL1317526 | 0.85 | NT5E (0.45) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL381896 | 0.84 | ST6GAL1 (0.38) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL5200171 | 0.83 | POLB (0.40) | ST6GAL1LMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239834-A1 | ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS | FUJIMOTO CHEMICALS CO., LTD., (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20240239833-A1 | ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS | FUJIMOTO CHEMICALS CO., LTD., (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20210317159-A1 | ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS | FUJIMOTO CHEMICALS CO., LTD. (JP) | 2021-10-14 | — | — | US | disclosed |
| EP-3825300-A1 | ALKOXYPHENYL DERIVATIVE, NUCLEOSIDE PROTECTOR, NUCLEOTIDE PROTECTOR, METHOD FOR PRODUCING OLIGONUCLEOTIDE, AND METHOD FOR REMOVING SUBSTITUENT | Fujimoto Chemicals Co. Ltd. (JP) | 2021-05-26 | — | — | EP | disclosed |
| EP-3004131-B1 | PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES | AM CHEMICALS LLC (US) | 2020-07-22 | — | — | EP | disclosed |
| US-10669301-B2 | Phosphoramidite building blocks for sugar-conjugated oligonucleotides | AM CHEMICALS LLC (US) | 2020-06-02 | — | — | US | disclosed |
| WO-2020017085-A1 | ALKOXYPHENYL DERIVATIVE, NUCLEOSIDE PROTECTOR, NUCLEOTIDE PROTECTOR, METHOD FOR PRODUCING OLIGONUCLEOTIDE, AND METHOD FOR REMOVING SUBSTITUENT | 藤本化学製品株式会社 | 2020-01-23 | — | — | WO | disclosed |
| US-20180362572-A1 | PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES | AM CHEMICALS LLC (US) | 2018-12-20 | — | — | US | disclosed |
| US-10087208-B2 | Phosphoramidite building blocks for sugar-conjugated oligonucleotides | AM CHEMICALS LLC (US) | 2018-10-02 | — | — | US | disclosed |
| US-20160083414-A1 | PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES | AM CHEMICALS LLC (US) | 2016-03-24 | — | — | US | disclosed |
| US-20030004325-A1 | Sugar modified oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2003-01-02 | — | — | US | disclosed |
| US-6399754-B1 | CONTAINING SULFOPHOSPHATE GROUP | ISIS PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |
| EP-0739902-B1 | H-Phosphonate ribonucleotide derivatives | ISIS PHARMACEUTICALS INC (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-0739900-B1 | Novel oligoribonucleotide derivatives and application thereof to antiviral agents | ISIS PHARMACEUTICALS INC (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-0739899-B1 | Novel oligoribonucleotide derivatives and application thereof to antiviral agents | ISIS PHARMACEUTICALS INC (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-0339842-B1 | Novel oligoribonucleotide derivatives and application thereof to antiviral agents | ISIS PHARMACEUTICALS INC (US) | 1996-11-06 | — | — | EP | disclosed |
| EP-0739901-A2 | Novel oligoribonucleotide derivatives and application thereof to antiviral agents | ISIS PHARMACEUTICALS, INC. (US) | 1996-10-30 | — | — | EP | disclosed |
| EP-0739902-A2 | Novel oligoribonucleotide derivatives and application thereof to antiviral agents | ISIS PHARMACEUTICALS, INC. (US) | 1996-10-30 | — | — | EP | disclosed |
| EP-0739899-A2 | Novel oligoribonucleotide derivatives and application thereof to antiviral agents | ISIS PHARMACEUTICALS, INC. (US) | 1996-10-30 | — | — | EP | disclosed |
| EP-0739900-A2 | Novel oligoribonucleotide derivatives and application thereof to antiviral agents | ISIS PHARMACEUTICALS, INC. (US) | 1996-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10669301-B2 | Phosphoramidite building blocks for sugar-conjugated oligonucleotides | DERA, FBP1, PNKP | ST6GAL1 319/4885NT5E 346/4885LMNA 3031/4885 |
| US-20180362572-A1 | PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES | DERA, TYMP, PAICS | ST6GAL1 583/4885NT5E 398/4885LMNA 3374/4885 |
| US-20240239834-A1 | ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS | ROS1, POLN, RNMT | ST6GAL1 3029/4885NT5E 210/4885LMNA 274/4885 |
| US-10087208-B2 | Phosphoramidite building blocks for sugar-conjugated oligonucleotides | DERA, TYMP, PAICS | ST6GAL1 583/4885NT5E 398/4885LMNA 3374/4885 |
| US-20210317159-A1 | ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS | ROS1, POLN, RNMT | ST6GAL1 3029/4885NT5E 210/4885LMNA 274/4885 |
| US-20240239833-A1 | ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS | ROS1, POLN, RNMT | ST6GAL1 3029/4885NT5E 210/4885LMNA 274/4885 |
| US-20160083414-A1 | PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES | DERA, TYMP, PAICS | ST6GAL1 583/4885NT5E 398/4885LMNA 3374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.