Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 1/20 | 0.52 |
| ▸ | HEXB | P07686 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694048 | 0.85 | HPGD (0.51) | HEXAHEXBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL14121833 | 0.79 | TSHR (0.66) | HEXAHEXBDRD2HTR1AHTR7 | |
| SCHEMBL11022908 | 0.79 | MAOB (0.56) | DRD2HTR1AHTR7BCHEACHE | |
| SCHEMBL10694245 | 0.78 | RAB9A (0.54) | HEXAHEXBCYP2D6HSD17B10HPGD | |
| SCHEMBL10691771 | 0.78 | HPGD (0.46) | DRD2ALDH1A1CYP3A4CYP2D6ALOX12 | |
| SCHEMBL10665907 | 0.78 | RAB9A (0.64) | ALDH1A1MEN1KMT2AMAOBHPGD | |
| SCHEMBL10688822 | 0.78 | SMN1; SMN2 (0.53) | ALDH1A1MEN1CYP2D6KMT2AHPGD | |
| SCHEMBL10692842 | 0.77 | MAPT (0.52) | CYP2D6HSD17B10HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL10695966 | 0.77 | MAPT (0.52) | CYP2D6HSD17B10HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL10696014 | 0.77 | MAPT (0.52) | CYP2D6HSD17B10HPGDSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |