Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1037738 | 1.00 | CES2 (0.59) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL11459441 | 1.00 | CES2 (0.59) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL11468377 | 1.00 | CES2 (0.59) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL5423233 | 0.98 | CES2 (0.56) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL11457223 | 0.91 | — | — | |
| SCHEMBL7028977 | 0.84 | CES2 (0.61) | CES2ALDH1A1TSHRCES1SLC22A6 | |
| SCHEMBL23950441 | 0.81 | CES2 (0.64) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL23950237 | 0.81 | CES2 (0.64) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL8773299 | 0.81 | CES2 (0.64) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL23950236 | 0.81 | CES2 (0.64) | CES2MEN1FAAHMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255424-A1 | Immunotoxins, process for preparing them and pharmaceutical compositions containing them | SANOFI (FR) | 1988-02-03 | — | — | EP | disclosed |