Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | IL2 | P60568 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30499684 | 0.84 | MAPT (0.62) | TRPA1TLR7LMNAMEN1KMT2A | |
| SCHEMBL7607258 | 0.84 | MAPT (0.62) | TRPA1TLR7LMNAMEN1KMT2A | |
| Penfluron SCHEMBL117735 | 0.81 | EPHX2 (0.60) | TRPA1TLR7CYP1A2MEN1KMT2A | |
| SCHEMBL11181555 | 0.80 | SMN1; SMN2 (0.58) | TLR7LMNAMEN1KMT2ANPC1 | |
| SCHEMBL9326300 | 0.79 | EPHX2 (0.57) | TRPA1TLR7CYP1A2MEN1KMT2A | |
| SCHEMBL9621859 | 0.78 | MEN1 (0.50) | TRPA1TLR7CYP1A2MEN1KMT2A | |
| SCHEMBL10934022 | 0.77 | KDM4E (0.52) | TLR7MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11100265 | 0.76 | HCRTR1 (0.61) | MEN1KMT2ARAB9ANPC1GAA | |
| SCHEMBL10525954 | 0.75 | TLR7 (0.62) | TLR8TRPA1TLR7CYP1A2MEN1 | |
| SCHEMBL29608194 | 0.75 | MEN1 (0.54) | TLR8TRPA1TLR7CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762928-A | PESTICIDES, MEDICINES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1988-08-09 | — | — | US | disclosed |
| EP-0228846-A1 | Amino-trifluoromethylpyridine compound and process for preparing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-07-15 | — | — | EP | disclosed |