Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621862 | 0.91 | TLR7 (0.62) | MEN1KMT2ATLR7NPC1RAB9A | |
| SCHEMBL10612883 | 0.83 | NPC1 (0.50) | MEN1KMT2AATMTRPA1NPC1 | |
| SCHEMBL6508343 | 0.82 | MEN1 (0.47) | MEN1KMT2AATMTRPA1TLR7 | |
| SCHEMBL30499684 | 0.82 | MAPT (0.62) | MEN1KMT2ATRPA1TLR7RAB9A | |
| SCHEMBL7607258 | 0.82 | MAPT (0.62) | MEN1KMT2ATRPA1TLR7RAB9A | |
| Penfluron SCHEMBL117735 | 0.81 | EPHX2 (0.60) | MEN1KMT2ATRPA1TLR7CYP1A2 | |
| SCHEMBL9622249 | 0.81 | AR (0.55) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL15335264 | 0.79 | MEN1 (0.59) | MEN1KMT2AATMTLR7NPC1 | |
| SCHEMBL15335265 | 0.79 | TRPA1 (0.59) | MEN1KMT2AATMTRPA1NPC1 | |
| SCHEMBL9326300 | 0.79 | EPHX2 (0.57) | MEN1KMT2ATRPA1TLR7CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096928-A | Caterpillars | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | claimed |
| JP-1168661-A | — | — | None | — | — | JP | disclosed |
| US-5096928-A | Caterpillars | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| JP-H01168661-A | SUBSTITUTED BENZOYL UREA AND THIOUREA | BAYER AG | 1989-07-04 | — | — | JP | disclosed |