Acrylic Acid Ethyl Ester

Acrylic Acid Ethyl Ester

SCHEMBL10693904

C=C(C)C(=O)OC(=O)C=CC=CC.C=C(C)C(=O)OCC1CO1.C=CC(=O)OCC.C=CC(=O)OCCCC

nearest known ligand 0.46

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TSHR P16473 4/20 0.41
HPGD P15428 1/20 0.41
ATM Q13315 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
CYP3A4 P08684 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Ethyl Ester SCHEMBL7639859 0.88 ALDH1A1 (0.59) ALDH1A1TSHRHPGDATMSMN1; SMN2
Acrylic Acid Ethyl Ester SCHEMBL10693901 0.88 ALDH1A1 (0.47) ALDH1A1TSHRHPGDATMSMN1; SMN2
Acrylic Acid Ethyl Ester SCHEMBL27718369 0.85 ALDH1A1 (0.56) ALDH1A1TSHRHPGDATMSMN1; SMN2
SCHEMBL10697765 0.85 ALDH1A1 (0.64) ALDH1A1TSHRCYP3A4
SCHEMBL221053 0.85 ALDH1A1 (0.64) ALDH1A1TSHRHPGDATMSMN1; SMN2
SCHEMBL29136554 0.84 ALDH1A1 (0.62) ALDH1A1TSHRHPGDATMSMN1; SMN2
Ethylene SCHEMBL3475332 0.84 ALDH1A1 (0.62) ALDH1A1TSHRHPGDATMSMN1; SMN2
Vinyl Chloride SCHEMBL28543043 0.82 ALDH1A1 (0.59) ALDH1A1TSHRHPGDATMSMN1; SMN2
Methacrylic Acid SCHEMBL4814817 0.82 ALDH1A1 (0.59) ALDH1A1TSHRHPGDATMSMN1; SMN2
SCHEMBL28233475 0.82 ALDH1A1 (0.59) ALDH1A1TSHRHPGDATMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4791181-A LOW CONCENTRATIONS OF ACETONITRILE USED TO CONTROL FORMATION OF LIVING POLYMERS BY BULK POLYMERIZATION IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-12-13 US disclosed