Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 4/20 | 0.48 |
| ▸ | GRK6 | P43250 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 4/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694101 | 0.84 | PARP1 (0.54) | CHEK2WNT3ATNKS2PARP1 | |
| SCHEMBL10696164 | 0.84 | PARP1 (0.54) | CHEK2ADORA1PARP1PLA2G2AALOX15 | |
| SCHEMBL9222388 | 0.82 | CHEK2 (0.35) | CHEK2ADORA1DHODH | |
| SCHEMBL10695803 | 0.82 | CHEK2 (0.47) | CHEK2TNKS2PARP1 | |
| SCHEMBL3559177 | 0.81 | CHEK2 (0.57) | CHEK2SCN9ADHODH | |
| SCHEMBL10694134 | 0.80 | PARP1 (0.50) | CHEK2TNKS2PARP1DHODH | |
| SCHEMBL10695465 | 0.79 | PARP1 (0.43) | CHEK2TNKS2PARP1DHODH | |
| SCHEMBL10696610 | 0.79 | KDM5A (0.42) | CHEK2GRK6SCN10ASCN9AADORA1 | |
| SCHEMBL10694623 | 0.79 | PARP1 (0.51) | CHEK2PARP1 | |
| Hydrochloric Acid SCHEMBL10695451 | 0.79 | PARP1 (0.49) | CHEK2TNKS2PARP1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269238-A1 | Imidazoles and their compositions for plant growth regulation | MAY & BAKER LIMITED (GB) | 1988-06-01 | — | — | EP | disclosed |
| EP-0253084-A2 | 1,3-Disubstituted imidazolium salts | F. HOFFMANN-LA ROCHE AG (CH) | 1988-01-20 | — | — | EP | disclosed |