Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.38 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.38 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 2/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694134 | 0.87 | PARP1 (0.50) | PARP1CHEK2TNKSTNKS2DHODH | |
| Hydrochloric Acid SCHEMBL10695451 | 0.86 | PARP1 (0.49) | PARP1CHEK2TNKSTNKS2DHODH | |
| SCHEMBL10695803 | 0.86 | CHEK2 (0.47) | PARP1CHEK2HDAC6TNKSTNKS2 | |
| SCHEMBL10695587 | 0.86 | CHEK2 (0.48) | PARP1CHEK2DHODH | |
| SCHEMBL10694623 | 0.86 | PARP1 (0.51) | PARP1CHEK2 | |
| SCHEMBL10695212 | 0.84 | PARP1 (0.52) | PARP1CHEK2MMP2MMP9MMP8 | |
| SCHEMBL10696406 | 0.84 | PIN1 (0.45) | PARP1HDAC6CDC7 | |
| SCHEMBL10694101 | 0.82 | PARP1 (0.54) | PARP1CHEK2TNKSTNKS2 | |
| SCHEMBL10696164 | 0.82 | PARP1 (0.54) | PARP1CHEK2 | |
| SCHEMBL10695184 | 0.82 | PARP1 (0.54) | PARP1CHEK2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269238-A1 | Imidazoles and their compositions for plant growth regulation | MAY & BAKER LIMITED (GB) | 1988-06-01 | — | — | EP | disclosed |